Vitan Side effects

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Side effects of Vitan in details

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Excessive doses of vitamin A to be the result of the symptoms are summarized as follows: - Acute hipervitaminöz A: Headache, dizziness, nausea, vomiting, weakness, infants fontanel swelling (Maria-see syndrome), adult brain pseudotumor, called benign intracranial hypertension in the form of intracranial an increase in pressure. - Chronic hipervitaminöz A: General Painting: Fatigue, lethargy, sleep disorders, mental disorders, hiperirritabilite, headache, anorexia, nausea and vomiting. Blood: The nose bleeding, rarely hypoprothrombinemia. Eye: Papilledema, the double vision. Skin and mucous membranes: epithelial tissue loss, itching, hair loss, skin dryness, lips cracking, Internal Organs: Hepatomegaly and more rare splenomegaly, Genital Organs: Menstrual disorders (very rare). Skeletal System: Bone and joint pain, cortical hiperostoz long bones, premature closure of epiphysis in children.

Vitan contraindications

The intravenous administration. Hypervitaminosis A. Sensitivity to any of the ingredients in this preparation. Use in Pregnancy: Safety of amounts exceeding 6,000 Units of vitamin A daily during pregnancy has not been established at this time. The use of vitamin A in excess of the recommended dietary allowance may cause fetal harm when administered to a pregnant woman. Animal reproduction studies have shown fetal abnormalities associated with overdosage in several species. Malformations of the central nervous system, the eye, the palate, and the urogenital tract are recorded. Vitan in excess of the recommended dietary allowance is contraindicated in women who are or may become pregnant. If vitamin A is used during pregnancy, or if the patient becomes pregnant while taking vitamin A, the patient should be apprised of the potential hazard to the fetus.


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References

  1. DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DTP/NCI. "retinol: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
  3. European Chemicals Agency - ECHA. "Retinol: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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